Author

Leidy C. Merselis

Bristol-Myers Squibb (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Laurel B. StineiD· 2 shared Stephen C. WilsoniD· 2 shared Alan F. CoriniD· 1 shared Alaric J. DyckmaniD· 1 shared Ali E. YesilkanaliD· 1 shared Amit Anand· 1 shared Ashish K. Singh· 1 shared Asmita Choudhury· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Laurel B. StineORCID

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2 papers

Recent·Most cited

CK2 directly controls CARD9 protein homeostasis

Aya M. Kelly, Leidy C. Merselis, Benjamin Causton, Olivia K. Calder, Hoson Chao, Margaret M. Prack, Laurel B. Stine, Yuka Amako, Tao Wang, Ali E. Yesilkanal, Kendall J. Condon, Meekyum O. Pierce, Scott H. Watterson, Jason M. Guernon, Amit Anand, , Stephen C. Wilson

This study identifies CK2 as a regulator of CARD9 protein stability, showing CK2 inhibition leads to CARD9 depletion and demonstrating therapeutic potential in vivo.

ACS Chemical Biology · May 16, 2026Peer-reviewedImmunology

Orthosteric STING inhibition elucidates molecular correction of SAVI STING

Tao Xie, Max Ruzanov, David Critton, Leidy C. Merselis, Joseph G. Naglich, John S. Sack, Ping Zhang, Chunshan Xie, Jeffrey A. Tredup, Laurel B. Stine, Cameron M. Messier, David L Hope, Janet Caceres‐Cortes, Luciano Mueller, Alaric J. Dyckman, , Stephen C. Wilson

This study identifies a critical residue for STING activation and shows how an orthosteric inhibitor can partially correct a SAVI mutation.

Nature Communications · Jul 1, 2025Peer-reviewedMolecular Biology