Author

Huaigu Sun

University of North Carolina at Chapel Hill

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Genetic & Genomic Medicine· 1 Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:Hi-C· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Andrea R.V.R. Horimoto· 1 shared Benxia HuiD· 1 shared Brian D. CheniD· 1 shared Bryan C. QuachiD· 1 shared Dana B. HancockiD· 1 shared Eric Otto JohnsoniD· 1 shared Gabriella Ben Hutta· 1 shared Geoffery W. Wang· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperGenetic & Genomic Medicine

Andrea R.V.R. Horimoto

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Retinal Transcriptome-Wide Association Study Identifies Novel Alzheimer's Disease Risk Genes

Yinuo Zhang, Brian D. Chen, Huaigu Sun, Ruhao Shi, Li Y, Jiawen Du, Andrea R.V.R. Horimoto

This study identifies 62 Alzheimer's disease-associated genes using retinal transcriptome-wide association studies and validates 31 in an independent cohort, highlighting immune dysregulation and novel risk genes.

medRxiv · Jul 4, 2026 · PreprintGenetic & Genomic Medicine

SnapHiC-G: identifying long-range enhancer-promoter interactions from single-cell Hi-C data via a global background model

Weifang Liu, Wujuan Zhong, Paola Giusti‐Rodríguez, Zhiyun Jiang, Geoffery W. Wang, Huaigu Sun, Ming Hu, Yun Li

SnapHiC-G identifies long-range enhancer-promoter interactions from scHi-C data using a global background model, showing high sensitivity and cell-type-specific enrichment of neuropsychiatric disease SNPs.

Briefings in Bioinformatics · Jul 25, 2024Peer-reviewedGenetics

Chromatin architecture in addiction circuitry elucidates biological mechanisms underlying cigarette smoking and alcohol use traits.

Nancy Y. A. Sey, Benxia Hu, Marina Iskhakova, Huaigu Sun, Neda Shokrian, Gabriella Ben Hutta, Jesse A. Marks, Bryan C. Quach, Eric Otto Johnson, Dana B. Hancock, Schahram Akbarian, Hyejung Won

The paper uses Hi-C data to link genetic risk variants for smoking and alcohol use to specific genes and pathways in brain regions involved in addiction.

bioRxiv · Mar 18, 2021 · PreprintNeuroscience