Author

Jesse A. Marks

RTI InternationalORCID 0000-0002-8159-3594Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:GWAS / association mapping· 2 Assay:GWAS summary statistics· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1

Frequent Co-Authors

Bryan C. QuachiD· 3 shared Dana B. HancockiD· 3 shared Eric Otto JohnsoniD· 3 shared Hyejung WoniD· 2 shared Laura Jean BierutiD· 2 shared Nancy Y. A. SeyiD· 2 shared Nathan GaddisiD· 2 shared Yuelong GuoiD· 2 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersGenetics

Bryan C. QuachORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Evaluation of methods incorporating biological function and GWAS summary statistics to accelerate discovery

Amy L Moore, Jesse A. Marks, Bryan C. Quach, Yuelong Guo, Laura Jean Bierut, Nathan Gaddis, Dana B. Hancock, Grier P. Page, Eric Otto Johnson

This study evaluates 18 functional weighting methods to enhance GWAS discovery, finding some methods can nominate high PPV variants for multiple traits without increasing sample size.

bioRxiv · Jan 10, 2022 · PreprintGenetics

Chromatin architecture in addiction circuitry elucidates biological mechanisms underlying cigarette smoking and alcohol use traits.

Nancy Y. A. Sey, Benxia Hu, Marina Iskhakova, Huaigu Sun, Neda Shokrian, Gabriella Ben Hutta, Jesse A. Marks, Bryan C. Quach, Eric Otto Johnson, Dana B. Hancock, Schahram Akbarian, Hyejung Won

The paper uses Hi-C data to link genetic risk variants for smoking and alcohol use to specific genes and pathways in brain regions involved in addiction.

bioRxiv · Mar 18, 2021 · PreprintNeuroscience

Expanding the Genetic Architecture of Nicotine Dependence and its Shared Genetics with Multiple Traits: Findings from the Nicotine Dependence GenOmics (iNDiGO) Consortium

Bryan C. Quach, Michael A. Bray, Nathan Gaddis, Mengzhen Liu, Teemu Palviainen, Camelia C. Minică, Stephanie M. Zellers, Richard Sherva, Fazil Alıev, Michael Nothnagel, Kendra A. Young, Jesse A. Marks, Hannah E. Young, Megan Ulmer Carnes, Yuelong Guo, , Dana B. Hancock

The paper identifies novel genetic loci associated with nicotine dependence and shows genetic correlations with other smoking traits and comorbidities using genome-wide association studies.

Nature Communications · Nov 3, 2020Peer-reviewedGenomics