Spatial mapping of cellular and molecular plasticity in the maternal and postpartum mouse brain
Keon Arbabi, Shahrzad Ghazisaeidi, Minjin Kim, Bharti Kukreja, Min Yi Feng, Spenser Pogue, Hugo Hudson, Maria Eleni Fafouti, Elizabeth L. Crouch, Liisa A.M. Galea, Shreejoy J. Tripathy, Brian Thomas Kalish
The paper maps cellular and molecular changes in the mouse brain during pregnancy and postpartum using spatial single-cell technologies, identifying three gene expression programs and linking depression risk genes to specific brain regions.
bioRxiv · Aug 21, 2026 · PreprintGenomics