Shahrzad Ghazisaeidi

Spatial mapping of cellular and molecular plasticity in the maternal and postpartum mouse brain

The paper maps cellular and molecular changes in the mouse brain during pregnancy and postpartum using spatial single-cell technologies, identifying three gene expression programs and linking depression risk genes to specific brain regions.

Meningeal macrophages mask incision pain sensitization in male rats

This study shows that CD206+ meningeal macrophages mask mechanical hypersensitivity in male rats after skin incision but not in females.

Conserved transcriptional programming across sex and species after peripheral nerve injury predicts treatments for neuropathic pain

The paper identifies conserved transcriptional changes across sex and species after peripheral nerve injury and predicts a new analgesic treatment using a drug-gene interactome analysis.

Regulation of neuropathic pain by microglial Orai1 channels

This study shows that Orai1 channels regulate microglial reactivity and neuropathic pain, with sexual dimorphism observed in their effects.