Relaxed DNA substrate specificity of transposases involved in programmed genome rearrangement
Matt W.G. Walker, Takahiko Akematsu, Erhan Aslan, Danylo Villano, Harrison S. Fried, Hui Lan, Samuel H. Sternberg, Laura F. Landweber
This study investigates the DNA recognition properties of transposases in Oxytricha trifallax using heterologous assays and ChIP-seq, revealing relaxed sequence specificity and precise nuclear localization during genome rearrangement.
Nucleic Acids Research · Jun 13, 2025Peer-reviewedMolecular Biology