Matt W.G. Walker

This study shows that temperate phages enhance bacterial fitness by remodeling flagella via RNA-guided transcription factors, improving motility and immune evasion.

This study investigates the DNA recognition properties of transposases in Oxytricha trifallax using heterologous assays and ChIP-seq, revealing relaxed sequence specificity and precise nuclear localization during genome rearrangement.

The paper demonstrates that bacterial reverse transcriptases synthesize extrachromosomal genes via rolling-circle amplification to confer antiviral immunity.

The paper identifies TnpB-like nuclease-dead repressors (TldR) as RNA-guided transcription factors that emerged through domestication of transposon-encoded TnpB nucleases, pre-dating CRISPR-Cas systems.

This study shows that transposon-encoded nucleases use guide RNAs to bias transposon inheritance by cleaving donor joints formed during transposition.

This study identifies sequence requirements for CRISPR-associated transposon DNA integration using mutagenesis libraries and reveals a novel role for IHF in transposition.