Author

Hui Qi Loo

Washington University in St. LouisPrimary ORCID profile (0000-0002-0390-9047 · 2 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Hui Qi LooiD2 papers · Emory University

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Neuroscience· 1

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Joseph BloomiD· 1 shared Aaron D. GitleriD· 1 shared Aaron DiAntonioiD· 1 shared Caiwei GuoiD· 1 shared Dennis W. DicksoniD· 1 shared James T. O’ConnoriD· 1 shared Jeffrey MilbrandtiD· 1 shared Leonard PetrucelliiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

A. Joseph BloomORCID

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1 paper

Recent·Most cited

TDP-43 suppression of ATP8A2 cryptic splicing implicates phosphatidylserine-driven neuroinflammation in ALS/FTD

James T. O’Connor, Hui Qi Loo, Caiwei Guo, Sarah R. Pickles, Shea Sundali, Vidhya Maheswari Jawahar, Dennis W. Dickson, A. Joseph Bloom, Leonard Petrucelli, Aaron D. Gitler, Jeffrey Milbrandt, Aaron DiAntonio

This study identifies ATP8A2 as a TDP-43 target whose loss leads to PS exposure and neuroinflammation, suggesting immune cell inhibition as a therapeutic strategy for ALS-FTD and CAMRQ4.

bioRxiv · Nov 21, 2025 · PreprintNeuroscience