Hussam Moammer

The absence of collagen VI reduces systolic function but paradoxically increases Ca2+ release in the rat heart

This study shows that collagen VI deficiency in rats reduces systolic function but increases Ca2+ release in cardiomyocytes, suggesting a role in Ca2+ signaling regulation.

Reverse remodelling of the mitochondria and cytoskeleton after respiratory heart rate variability pacing of the failing sheep heart

This study shows that respiratory heart rate variability pacing improves cardiac output in failing sheep hearts by restoring mitochondrial function and cytoskeletal structure.