High-resolution cryo-EM structures of small protein-ligand complexes near the theoretical size limit
Kunwoong Park, Youngki Yoo, Hyunbum Jeon, Kiju Choi, Hanseong Kim, Eunju Kwon, Hyun–Ho Lim, Dong Young Kim, Kyoung Tai No
This study reports cryo-EM structures of two small protein-ligand complexes near the theoretical size limit of 38 kDa, demonstrating cryo-EM's utility for structure determination and drug screening.
Nature Communications · Apr 14, 2026Peer-reviewedBiophysics