Author

I. Abramovitch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

E. Gottlieb· 2 shared A. C. Finney· 1 shared A. Ghrayeb· 1 shared A. Saragovi· 1 shared B. Agranovich· 1 shared D. Peled· 1 shared E. Arbib· 1 shared I. Mor· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

E. Gottlieb

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2 papers

Recent·Most cited

Fatty liver-mediated glycine restriction impairs glutathione synthesis and causes hypersensitization to acetaminophen

A. Ghrayeb, B. Agranovich, D. Peled, A. C. Finney, I. Abramovitch, J. Fernandez Garcia, J. G. Traylor, S. Drucker, S. I. Fernandes, N. Weissman, Y. E. Chen, O. Rom, I. Mor, E. Gottlieb

This study shows fatty liver reduces glycine, impairing glutathione synthesis and increasing sensitivity to acetaminophen toxicity in mice.

bioRxiv · Jan 16, 2023 · PreprintBiochemistry

Systemic hypoxia inhibits T cell response by limiting mitobiogenesis via matrix substrate-level phosphorylation arrest

A. Saragovi, I. Abramovitch, O. Toker, E. Arbib, I. Omar, E. Gottlieb, M. Berger

This study shows that systemic hypoxia impairs CD8+ T cell responses by inhibiting mitochondrial biogenesis, which can be rescued by TCA cycle re-stimulation or brief oxygen exposure.

bioRxiv · Mar 19, 2020Immunology