Mechanistic and evolutionary insights into isoform-specific 'supercharging' in DCLK family kinases
A. Venkat, G. Watterson, D. P. Byrne, B. O. Boyle, S. Shrestha, N. Gravel, E. E. Fairweather, L. A. Daly, C. Bunn, W. Yeung, I. Aggarwal, S. Katiyar, C. E. Eyers, P. Eyers, N. Kannan
This study investigates how isoform-specific variations in DCLK family kinases affect autoregulation through structural and functional analyses.
bioRxiv · Mar 29, 2023Evolutionary Biology