Bile canaliculi contract autonomously by releasing calcium into hepatocytes via mechanosensitive calcium channel
K. Gupta, I. C. Ng, B. P. Nguyen, L. Tucker-Kellogg, B. C. Low, H. Yu
The paper shows bile canaliculi contract by releasing calcium into hepatocytes via mechanosensitive channels, driven by bile pressure and regulated by Piezo-1.
bioRxiv · Oct 22, 2018Cell Biology