Author

I. Dobrescu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1 Organism:plant (other)· 1

Frequent Co-Authors

A. Scherf· 2 shared F. Nardella· 2 shared L. Halby· 2 shared P. B. Arimondo· 2 shared A. Claës· 1 shared A. Lorthiois· 1 shared A. Tafit· 1 shared B. Witkowski· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersPharmacology & Toxicology

A. Scherf

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Quinazoline-quinoline bisubstrate inhibitors target eukaryotic translation initiation factor 3 in Plasmodium falciparum

I. Dobrescu, E. Hammam, J. M. Dziekan, A. Claës, L. Halby, P. Preiser, Z. Bozdech, P. B. Arimondo, A. Scherf, F. Nardella

This study identifies PfEIF3i as a target of quinoline-quinazoline inhibitors in Plasmodium falciparum, showing its essential role in parasite development and potential as an antimalarial drug target.

bioRxiv · Dec 10, 2022 · PreprintPharmacology & Toxicology

Hemisynthetic derivatives of the natural alkaloid trilobine are fast-acting antimalarial compounds with sustained activity in multi-drug resistant P. falciparum isolates

F. Nardella, I. Dobrescu, H. Hassan, F. Rodrigues, S. Thiberge, L. Mancio, A. Tafit, C. Jallet, V. Cadet-Daniel, S. Goussin, A. Lorthiois, Y. Menon, N. Molinier, D. Pechalrieu, C. Long, , P. B. Arimondo

bioRxiv · Aug 30, 2022 · PreprintPathology