H. Hassan

Potential role of microRNAs in regulating transcriptional profile, and sculpting development and metabolism in cavefish.

This study identifies 683 miRNAs in cavefish, revealing their role in regulating development and metabolism through differential expression and pathway involvement.

3D spheroid culturing of Astyanax mexicanus liver-derived cell lines recapitulates distinct transcriptomic and metabolic states of in vivo tissue environment.

This study uses 3D spheroid culturing to model metabolic and transcriptomic states of Astyanax mexicanus liver cells, revealing cave-specific metabolic signatures.

Emergence of the Novel Infectious bursal disease viruse Variant in Vaccinated Poultry Flocks in Egypt

The paper reports the emergence of a novel IBDV variant in Egyptian poultry farms in 2023, causing subclinical infections and immunosuppression, with genetic features distinct from previous strains.

The Mexican Cavefish Mount a Rapid and Sustained Regenerative Response Following Skeletal Muscle Injury

The paper investigates the regenerative response of skeletal muscle in Mexican cavefish following injury, focusing on satellite cell behavior and regeneration mechanisms.

Circadian rhythm disruption is associated with skeletal muscle dysfunction within the blind Mexican Cavefish

This study investigates circadian-regulated gene expression in skeletal muscle of cavefish and surface fish to determine if muscle dysfunction is due to circadian disruption.

Comprehensive multi-omics characterization of gut microbiome extracellular vesicles reveals a connection to gut-brain axis signaling

This study characterizes gut microbiome extracellular vesicles through multi-omics approaches, revealing their role in delivering neuroactive molecules across gut and blood-brain barriers.

Hemisynthetic derivatives of the natural alkaloid trilobine are fast-acting antimalarial compounds with sustained activity in multi-drug resistant P. falciparum isolates

Liver-derived cell lines from cavefish Astyanax mexicanus as an in vitro model for studying metabolic adaptation

The paper develops liver-derived cell lines from cavefish Astyanax mexicanus to study metabolic adaptation and provides their characterization.

Metabolic reprogramming underlies cavefish muscular endurance despite loss of muscle mass and contractility

This paper shows cavefish have reduced muscle mass and contractility but increased muscular endurance due to metabolic reprogramming involving glycogen utilization.