Somatic hypomethylation of pericentromeric SST1 repeats and tetraploidization in human colorectal cancer cells
B. Gonzalez, M. Navarro-Jimenez, M. J. Alonso-De Gennaro, S. M. Jansen, I. Granada, M. Perucho, S. Alonso
The paper links SST1 hypomethylation with tetraploidization in human colorectal cancer cells and associates severe SST1 demethylation with TP53 mutations in primary CRC.
bioRxiv · Feb 19, 2021Cancer Biology