B. Gonzalez

New Features Surrounding the Cdc42-Ste20 Module that Regulates MAP Kinase Signaling in Yeast

This study identifies new regulatory features of the Cdc42-Ste20 module in yeast MAPK signaling, including Ste20p turnover and a Ste20p-independent pathway branch.

Exploring the Regulation of Cdc42 Stability and Turnover in Yeast

This paper identifies high temperature-induced degradation of yeast Cdc42p via ubiquitin ligase and chaperones, revealing a tradeoff between mating sensitivity and cellular fitness.

Turnover Regulation of the Rho GTPase Cdc42 by Heat Shock Protein Chaperones and the MAPK Pathway Scaffold Bem4

This paper shows that the yeast Rho GTPase Cdc42p is turned over by HSPs and the E3 ligase Rsp5p, with implications for cell polarity and MAPK pathway specificity.

Somatic hypomethylation of pericentromeric SST1 repeats and tetraploidization in human colorectal cancer cells

The paper links SST1 hypomethylation with tetraploidization in human colorectal cancer cells and associates severe SST1 demethylation with TP53 mutations in primary CRC.

Spatiotemporal Control of Pathway Sensors and Cross-Pathway Feedback Regulate a Cell Differentiation MAPK Pathway in Yeast

The paper shows that temporal and spatial regulation of pathway sensors and cross-pathway feedback control the fMAPK pathway in yeast.

Arabidopsis thaliana interaction with Ensifer meliloti can support plant growth under N-deficiency

This study shows that Arabidopsis thaliana can benefit from interaction with Ensifer meliloti under nitrogen deficiency, completing its life cycle through bacterial nitrogen fixation.