Spike protein disulfide disruption as a potential treatment for SARS-CoV-2
A. M. Grishin, N. V. Dolgova, S. Harms, I. J. Pickering, G. N. George, D. Falzarano, M. Cygler
This paper shows that reducing disulfide bonds in the SARS-CoV-2 Spike protein inhibits viral entry and replication, suggesting a potential antiviral treatment.
bioRxiv · Jan 2, 2021 · PreprintMicrobiology