Author

M. Cygler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. M. Grishin· 1 shared C. Giogha· 1 shared D. Falzarano· 1 shared E. Hartland· 1 shared G. N. George· 1 shared I. J. Pickering· 1 shared I. Yeuk Wah Chung· 1 shared J. Newson· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperMicrobiology

A. M. Grishin

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The porphyran degradation system is complete, phylogenetically and geographically diverse across the gut microbiota of East Asian populations

L. Segurel, T. S. Ulaganathan, S. Mathieu, M. Loiodice, L. Poulet, S. Drouillard, M. Cygler, W. Helbert

The paper identifies a porphyran degradation system in the gut microbiota of East Asian populations, showing its genetic diversity and geographic restriction to East Asia.

bioRxiv · Mar 30, 2023Biochemistry

Spike protein disulfide disruption as a potential treatment for SARS-CoV-2

A. M. Grishin, N. V. Dolgova, S. Harms, I. J. Pickering, G. N. George, D. Falzarano, M. Cygler

This paper shows that reducing disulfide bonds in the SARS-CoV-2 Spike protein inhibits viral entry and replication, suggesting a potential antiviral treatment.

bioRxiv · Jan 2, 2021 · PreprintMicrobiology

Salmonella effectors SseK1 and SseK3 target death domain proteins in the TNF and TRAIL signaling pathways

J. Newson, N. Scott, I. Yeuk Wah Chung, T. Wong Fok Lung, C. Giogha, N. Wang, R. Strugnell, N. Brown, M. Cygler, J. Pearson, E. Hartland

This study identifies that Salmonella effectors SseK1 and SseK3 glycosylate death domain proteins in TNF and TRAIL signaling pathways, modulating their function during infection.

bioRxiv · Jun 29, 2018Microbiology