Author

I. Levitan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Organism:mouse· 1

Frequent Co-Authors

A. A. Mongin· 1 shared A. Paul· 1 shared A. Sitikov· 1 shared B. A. Miao· 1 shared B. Chen· 1 shared C. Buasakdi· 1 shared C. Stanton· 1 shared D. Lazarko· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCell Biology

A. A. Mongin

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3 papers

Recent·Most cited

The Glycolytic Metabolite Methylglyoxal Covalently Inactivates the NLRP3 Inflammasome.

C. Stanton, C. Buasakdi, J. Sun, I. Levitan, P. Bora, S. Kutseikin, L. Wiseman, M. Bollong

This study shows methylglyoxal, a glycolytic metabolite, covalently inactivates the NLRP3 inflammasome by forming crosslinks, thereby reducing inflammation.

bioRxiv · Apr 19, 2024Cell Biology

Endothelial stiffening induced by CD36-mediated lipid uptake leads to endothelial barrier disruption and contributes to atherosclerotic lesions

V. Aguilar, E. Le Master, A. Paul, S. J. Ahn, D. Lazarko, M. Febbraio, J. C. Lee, I. Levitan

This study shows that CD36-mediated lipid uptake causes endothelial stiffening, leading to barrier disruption and atherosclerosis in mouse models, with sex-dependent effects.

bioRxiv · Nov 8, 2023Cell Biology

Anoctamin-1 is induced by TGF-beta and contributes to lung myofibroblast differentiation

E. B. Reed, S. Orbeta, B. A. Miao, A. Sitikov, B. Chen, I. Levitan, J. Solway, G. M. Mutlu, Y. Fang, A. A. Mongin, N. O. Dulin

This study shows TGF-beta induces ANO1 in lung fibroblasts, which increases intracellular chloride and activates WNK1 to promote myofibroblast differentiation and fibrosis.

bioRxiv · Jun 7, 2023Cell Biology