Pharmacology & ToxicologybioRxiv
The CB1 Negative Allosteric Modulator PSNCBAM-1 Reduces Ethanol Self-Administration via a Nonspecific Hypophagic Effect
H. M. Buechler, M. Sumi, I. M. Madhurathakam…·T. M. Keck
This study evaluates PSNCBAM-1, a CB1 negative allosteric modulator, in rodent models of AUD and finds it reduces ethanol self-administration via a nonspecific hypophagic effect without affecting ethanol reward.
DOI 10.1016/j.pbb.2024.173776