Unveiling the Molecular Mechanisms of the Type-IX Secretion System's Response Regulator: Structural and Functional Insights
A. Saran, H.-M. Kim, I. Manning, M. A. Hancock, C. Schmitz, M. Madej, J. Potempa, M. Sola, J.-F. Trempe, Y. Zhu, M. Davey, N. Zeytuni
This study characterizes PorX, a response regulator in the Type-IX secretion system, revealing its unique enzymatic activity and zinc-dependent dimerization, with implications for virulence factor secretion in bacterial pathogens.
bioRxiv · May 15, 2024Biochemistry