Author

A. Saran

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

C. Schmitz· 1 shared E. A. Fon· 1 shared E. MacDougall· 1 shared G. Kozlov· 1 shared G. Sung· 1 shared H.-M. Kim· 1 shared I. Manning· 1 shared J. Potempa· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiochemistry

C. Schmitz

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2 papers

Recent·Most cited

Unveiling the Molecular Mechanisms of the Type-IX Secretion System's Response Regulator: Structural and Functional Insights

A. Saran, H.-M. Kim, I. Manning, M. A. Hancock, C. Schmitz, M. Madej, J. Potempa, M. Sola, J.-F. Trempe, Y. Zhu, M. Davey, N. Zeytuni

This study characterizes PorX, a response regulator in the Type-IX secretion system, revealing its unique enzymatic activity and zinc-dependent dimerization, with implications for virulence factor secretion in bacterial pathogens.

bioRxiv · May 15, 2024Biochemistry

Structural basis for feedforward control in the PINK1/parkin pathway

V. Sauve, G. Sung, E. MacDougall, G. Kozlov, A. Saran, R. Fakih, E. A. Fon, K. Gehring

The paper elucidates how phospho-ubiquitin binds to parkin's RING domains to activate the PINK1/parkin pathway through a feedforward mechanism.

bioRxiv · Aug 16, 2021Biochemistry