Dynamic relocalization of the cytosolic type III secretion system components prevents premature protein secretion at low external pH
S. Wimmi, A. Balinovic, H. Jeckel, L. Selinger, D. Lampaki, E. Eisemann, I. Meuskens, D. Linke, K. Drescher, U. Endesfelder, A. Diepold
The paper shows that cytosolic T3SS components in gastrointestinal pathogens relocalize at low pH to prevent premature secretion, and this effect reverses at neutral pH.
bioRxiv · Apr 7, 2020Microbiology