A. Diepold

Repertoire and abundance of secreted virulence factors shape the pathogenic capacity of Pseudomonas syringae pv. aptata

This study identifies strain-specific secretome features in Pseudomonas syringae pv. aptata that correlate with pathogenicity.

Distinct cytosolic complexes containing the type III secretion system ATPase resolved by 3D single-molecule tracking in live Yersinia enterocolitica

This study uses 3D single-molecule tracking to identify distinct cytosolic complexes of injectisome proteins in live Yersinia enterocolitica cells, revealing their interactions and abundance.

Pilotins are mobile T3SS components involved in assembly and substrate specificity of the bacterial type III secretion system

The paper investigates the role of pilotins in T3SS assembly and substrate specificity, finding they are mobile and affect early substrate export but not late substrates.

Visualization of bacterial type 3 secretion system components down to the molecular level by MINFLUX nanoscopy

The paper uses MINFLUX nanoscopy to visualize T3SS components at high resolution, revealing structural details of bacterial virulence factors.

Dynamic relocalization of the cytosolic type III secretion system components prevents premature protein secretion at low external pH

The paper shows that cytosolic T3SS components in gastrointestinal pathogens relocalize at low pH to prevent premature secretion, and this effect reverses at neutral pH.

LITESEC-T3SS - Light-controlled protein delivery into eukaryotic cells with high spatial and temporal resolution

This study develops LITESEC-T3SS, a light-controlled system for precise and reversible protein translocation into eukaryotic cells using the T3SS.

Flagellar stators stimulate c-di-GMP production by Pseudomonas aeruginosa

This study shows that flagellar stators in Pseudomonas aeruginosa stimulate c-di-GMP production, creating a feedback loop that regulates motility and biofilm formation.

Visualization and regulation of translocons in Yersinia type III protein secretion machines during host cell infection

This study visualizes Yersinia translocons during host infection using superresolution microscopy and shows their regulation by host factors like Rac1.

Single-molecule tracking in live Yersinia enterocolitica reveals distinct cytosolic complexes of injectisome subunits

The paper uses single-molecule tracking to show SctQ and SctL form stable cytosolic complexes, revealing dynamic regulatory mechanisms in type 3 secretion.