H. Jeckel

Evolution of genotypic and phenotypic diversity in multispecies biofilms

This study shows how interspecies interactions in biofilms drive phenotypic diversity in Bacillus thuringiensis, with mutations in spo0A affecting matrix production and coexistence with Pseudomonas species.

Multispecies phase diagram of biofilm architectures reveals biophysical principles of biofilm development

The paper identifies two control parameters, cellular aspect ratio and cell density, that determine biofilm architecture across four bacterial species through experiments, simulations, and statistical analysis.

Vibrio cholerae biofilm dispersal regulator causes cell release from matrix through type IV pilus retraction

This study identifies VbdR as a regulator of Vibrio cholerae biofilm dispersal, showing it induces type IV pilus retraction and matrix protease expression to release cells from the biofilm matrix.

Spatial alanine metabolism determines local growth dynamics of Escherichia coli colonies

This study investigates spatial alanine metabolism in E. coli biofilms, revealing distinct metabolic roles in different regions that influence colony growth and morphology.

Dynamic relocalization of the cytosolic type III secretion system components prevents premature protein secretion at low external pH

The paper shows that cytosolic T3SS components in gastrointestinal pathogens relocalize at low pH to prevent premature secretion, and this effect reverses at neutral pH.

Flow-induced symmetry breaking in growing bacterial biofilms

This study investigates how fluid flow affects bacterial biofilm growth by combining live imaging and modeling, revealing three distinct growth phases and symmetry changes.

BiofilmQ, a software tool for quantitative image analysis of microbial biofilm communities

BiofilmQ is a software tool that enables automated, high-throughput quantitative analysis of 3D and 2D microbial biofilm communities through image cytometry.