Author

I. Morotti

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Physiology· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:rat· 1 Assay:structural biology· 1 Research Focus:synaptic & neural circuits· 1

Frequent Co-Authors

G. Piazzesi· 1 shared I. Pertici· 1 shared M. Caremani· 1 shared M. Linari· 1 shared M. Marcello· 1 shared M. Reconditi· 1 shared N. Theyencheri· 1 shared P. Bianco· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperPhysiology

G. Piazzesi

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1 paper

Recent·Most cited

An integrated picture of the structural pathways controlling the heart performance

I. Morotti, M. Caremani, M. Marcello, I. Pertici, P. Bianco, N. Theyencheri, G. Piazzesi, M. Reconditi, V. Lombardi, M. Linari

The paper revises the mechanosensing hypothesis of heart function using X-ray diffraction data and cryo-EM structures, identifying structural changes in thick filaments that modulate motor activation and heart performance.

Proceedings of the National Academy of Sciences · Dec 10, 2024Peer-reviewedPhysiology