N-terminal acetylation controls multiple functional aspects of the influenza A virus ribonuclease PA-X
R. E. Daly, C. Y. Feng, C. R. Hesser, I. Myasnikov, M. M. Gaglia
This paper investigates how N-terminal acetylation of the influenza A virus protein PA-X affects its nuclear localization and host shutoff activity, revealing that acetylation of the initiator methionine is specifically required for host shutoff.
bioRxiv · Dec 1, 2023Microbiology