Role of astrogial Connexin 43 in pneumococcal meningitis and pneumolysin cytotoxicity
C. Bello, Y. Smail, V. Sainte-Rose, I. Podglajen, A. Gilbert, V. Oliveira Moreira, F. Chretien, M. Cohen-Salmon, G. Tran Van Nhieu
This study shows that astrocytic connexin 43 facilitates pneumococcal meningitis by promoting bacterial translocation and cytosolic calcium increase through pneumolysin action.
bioRxiv · Jan 15, 2020 · PreprintMicrobiology