Author

F. Chretien

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Organism:non-human primate· 1

Frequent Co-Authors

A. Cachia· 1 shared A. Gilbert· 1 shared A.-C. Petit· 1 shared C. Bello· 1 shared D. Attali· 1 shared E. Simon-Loriere· 1 shared F. Perin-Dureau· 1 shared F. Vinckier· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. Cachia

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Inhibition of the replication of SARS-CoV-2 in human cells by the FDA-approved drug chlorpromazine

M. Plaze, D. Attali, M. Prot, A.-C. Petit, M. Blatzer, F. Vinckier, L. Levillayer, F. Perin-Dureau, A. Cachia, G. Friedlander, F. Chretien, E. Simon-Loriere, R. Gaillard

This study tests chlorpromazine's antiviral effect on SARS-CoV-2 in human and monkey cells, finding an IC50 of ~10M and suggesting its potential repurposing for COVID-19 treatment.

bioRxiv · May 5, 2020Microbiology

Role of astrogial Connexin 43 in pneumococcal meningitis and pneumolysin cytotoxicity

C. Bello, Y. Smail, V. Sainte-Rose, I. Podglajen, A. Gilbert, V. Oliveira Moreira, F. Chretien, M. Cohen-Salmon, G. Tran Van Nhieu

This study shows that astrocytic connexin 43 facilitates pneumococcal meningitis by promoting bacterial translocation and cytosolic calcium increase through pneumolysin action.

bioRxiv · Jan 15, 2020 · PreprintMicrobiology