Author

I. Popescu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Barcu· 1 shared A. Das· 1 shared A. H. Wells· 1 shared A. Morris· 1 shared A. Serban· 1 shared B. B. Chen· 1 shared B. J. McVerry· 1 shared B. Johnson· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBioengineering

A. Barcu

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2 papers

Recent·Most cited

A two-compartment system for subfreezing temperatures preservation of large volumes of organic matter in an isochoric system

G. Nastase, F. Botea, G. A. Beschea, S. I. Campean, A. Barcu, I. Popescu, B. Rubinsky, A. Serban

This paper describes a two-compartment isochoric system for supercooling large biological organs without ice nucleation, showing successful preservation of pig liver in vitro.

bioRxiv · Aug 31, 2022 · PreprintBioengineering

CD4+ T cell lymphopenia and dysfunction in severe COVID-19 disease is autocrine TNF-α/TNFRI-dependent

I. Popescu, M. E. Snyder, C. J. Iasella, S. J. Hannan, R. Koshy, R. Burke, A. Das, M. J. Brown, E. J. Lyons, S. C. Lieber, X. Chen, J. C. Sembrat, X. An, K. Linstrum, G. Kitsios, , J. F. McDyer

The paper shows that autocrine TNF-α/TNFRI signaling drives CD4+ T cell lymphopenia and dysfunction in severe COVID-19, and TNF-α blockade improves outcomes.

bioRxiv · Jun 2, 2021 · PreprintImmunology