Author

J. F. McDyer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2

Frequent Co-Authors

D. J. Kass· 2 shared J. K. Alder· 2 shared A. Das· 1 shared A. H. Wells· 1 shared A. Morris· 1 shared A. Prasse· 1 shared B. B. Chen· 1 shared B. J. McVerry· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

D. J. Kass

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2 papers

Recent·Most cited

High CXCL6 drives matrix expression and correlate with markers of poor outcome in IPF

H. Bahudhanapati, J. Tan, R.-M. Apel, B. Seeliger, X. Li, T.-Y. Chen, D. Sullivan, J. Sembrat, M. Rojas, E. Valenzi, R. A. Lafyatis, C. Jawale, P. Biswas, J. Tedrow, T. S. Adams, , D. J. Kass

This study identifies CXCL6 as a pro-fibrotic factor in IPF, showing it reduces cAMP, increases collagen and -SMA, and correlates with poor patient survival.

bioRxiv · Jun 22, 2021 · PreprintCell Biology

CD4+ T cell lymphopenia and dysfunction in severe COVID-19 disease is autocrine TNF-α/TNFRI-dependent

I. Popescu, M. E. Snyder, C. J. Iasella, S. J. Hannan, R. Koshy, R. Burke, A. Das, M. J. Brown, E. J. Lyons, S. C. Lieber, X. Chen, J. C. Sembrat, X. An, K. Linstrum, G. Kitsios, , J. F. McDyer

The paper shows that autocrine TNF-α/TNFRI signaling drives CD4+ T cell lymphopenia and dysfunction in severe COVID-19, and TNF-α blockade improves outcomes.

bioRxiv · Jun 2, 2021 · PreprintImmunology