Integrative genome-wide analysis reveals EIF3A as a key downstream regulator of translational repressor protein Musashi 2 (MSI2)
S. Karmakar, O. Ramirez, K. V. Paul, A. K. Gupta, V. Botti, I. R. d. l. Mozos, N. Neuenkirchen, R. J. Ross, K. M. Neugebauer, M. M. Pillai
The paper identifies EIF3A as a direct target of MSI2 and shows that MSI2 represses EIF3A translation, which amplifies its effects on the proteome.
bioRxiv · Feb 6, 2021Cancer Biology