Author

I. Raote

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 5 Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2 Approach:mechanistic / dynamical model· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

V. Malhotra· 5 shared F. Campelo· 2 shared F. Pincet· 2 shared A. Liu· 1 shared A. M. Ernst· 1 shared B. Cui· 1 shared B. El Haddouti· 1 shared C. Rabouille· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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5 shared papersCell Biology

V. Malhotra

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Endoplasmic reticulum exit sites are segregated for secretion based on cargo size

S. Saxena, O. Foresti, A. Liu, S. Androulaki, M. P. Rodriguez, I. Raote, B. Cui, M. Aridor, V. Malhotra

The paper shows that ERES segregate based on cargo size, with bulky cargoes accumulating less at stalled ERES compared to small molecules.

bioRxiv · Dec 7, 2023Cell Biology

A model for collagen secretion by intercompartmental continuities

L. Bunel, L. Pincet, V. Malhotra, I. Raote, F. Pincet

The paper proposes a mechanical/entropic ratchet model explaining how procollagen is exported from the ER via TANGO1-dependent tunnels using molecular gradients of pH and HSP47.

bioRxiv · Sep 21, 2023 · PreprintBiophysics

A physical mechanism of TANGO1-mediated bulky cargo export

I. Raote, M. Chabanon, N. Walani, M. Arroyo, M. F. Garcia-Parajo, V. Malhotra, F. Campelo

This paper presents a physical model explaining how TANGO1 stabilizes ER membrane tension to facilitate procollagen export from the ER.

bioRxiv · Jun 1, 2020Biophysics

GORASPs link Golgi cisternae laterally to stabilize the rims and prevent vesiculation

R. Grond, T. Veenendaal, J. Duran, I. Raote, S. Corstjens, L. Delfgou, B. El Haddouti, V. Malhotra, C. Rabouille

This study shows that GORASPs link Golgi cisternae laterally, stabilizing rims and preventing vesiculation in mice.

bioRxiv · Apr 28, 2020Cell Biology

TANGO1 membrane helices create a lipid diffusion barrier at curved membranes

I. Raote, A. M. Ernst, F. Campelo, J. E. Rothman, F. Pincet, V. Malhotra

The paper shows TANGO1 membrane helices form a lipid diffusion barrier at curved membranes to prevent mixing during secretory cargo transport.

bioRxiv · Apr 15, 2020Cell Biology