Eosinophil deficiency promotes aberrant repair and adverse remodelling following acute myocardial infarction
I. S. Toor, D. Ruckerl, I. Mair, R. Ainsworth, M. Meloni, A.-M. Spiroski, J. M. Felton, A. Thomson, A. Caporali, T. Keeble, K. Tang, A. G. Rossi, D. E. Newby, J. E. Allen, G. A. Gray
This study shows that eosinophil deficiency after myocardial infarction leads to adverse cardiac remodeling, which can be mitigated by IL-4 therapy.
bioRxiv · Sep 9, 2019Immunology