Author

I. Sambruni

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1

Frequent Co-Authors

C. Barone· 1 shared F. Alessandrini· 1 shared L. Ricci-Vitiani· 1 shared L. Rigoldi· 1 shared M. Buccarelli· 1 shared M. Pagin· 1 shared P. Malatesta· 1 shared R. Favaro· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

C. Barone

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1 paper

Recent·Most cited

Sox2-dependent maintenance of mouse oligodendroglioma involves the Sox2-mediated downregulation of Cdkn2b, Ebf1, Zfp423 and Hey2

C. Barone, M. Buccarelli, F. Alessandrini, M. Pagin, L. Rigoldi, I. Sambruni, R. Favaro, S. Ottolenghi, R. Pallini, L. Ricci-Vitiani, P. Malatesta, S. K. Nicolis

This study identifies four genes, Cdkn2b, Ebf1, Zfp423, and Hey2, whose inhibition by Sox2 is critical for maintaining glioma cancer stem cell properties, suggesting new therapeutic targets.

bioRxiv · Mar 4, 2020Cancer Biology