BiophysicsbioRxiv
Emergent chirality in active solid rotation of pancreas spheres
T. H. Tan, A. Amiri, I. Seijo-Barandiaran…·F. Jülicher
This study investigates how 3D geometry and topology influence collective cell dynamics in pancreatic organoids, revealing spontaneous chiral symmetry breaking through topological defects in traction forces.
DOI 10.1103/prxlife.2.033006