Author

I. T. Hoffecker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Research Focus:spatial domain detection· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:dimensionality reduction· 1 Assay:DNA methylation· 1 Organism:human· 1

Frequent Co-Authors

B. Högberg· 2 shared G. Bernardinelli· 2 shared A. I. Teixeira· 1 shared A. Shaw· 1 shared B. Hogberg· 1 shared E. Ambrosetti· 1 shared H. Iwata· 1 shared I. Smyrlaki· 1 shared

Activity by Year

2018-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersBiophysics

B. Högberg

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The geometric determinants of programmed antibody migration and binding on multi-antigen substrates

I. T. Hoffecker, A. Shaw, V. Sorokina, I. Smyrlaki, B. Högberg

The paper develops a model to simulate antibody-antigen interactions on patterned surfaces and shows antigen spacing influences antibody migration and binding.

bioRxiv · Oct 12, 2020 · PreprintBiophysics

A DNA nanoassembly-based approach to map membrane protein nanoenvironments

E. Ambrosetti, G. Bernardinelli, I. T. Hoffecker, L. Hartmanis, R. Sandberg, B. Hogberg, A. I. Teixeira

The paper introduces NanoDeep, a DNA nanoassembly-based method to map membrane protein nanoenvironments, revealing similar occupancy patterns of Her2, Her3, and EGFR in different cell lines and changes upon Heregulin-{beta}1 treatment.

bioRxiv · Nov 8, 2019Bioengineering

Tuning intercellular cohesion with membrane-anchored oligonucleotides

I. T. Hoffecker, Y. Arima, H. Iwata

This study introduces artificial cell-cell cohesion using membrane-anchored oligonucleotides and demonstrates tunable control over doublet geometry.

bioRxiv · Apr 27, 2019Biophysics

A Computational Framework for DNA Sequencing-Based Microscopy

I. T. Hoffecker, Y. Yang, G. Bernardinelli, P. Orponen, B. Högberg

The paper introduces a computational framework to reconstruct spatial information from DNA sequencing data by analyzing polony adjacency networks.

bioRxiv · Nov 21, 2018 · PreprintBiophysics