Author

I. Smyrlaki

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Assay:proteomics· 1

Frequent Co-Authors

B. Högberg· 2 shared A. I. Teixeira· 1 shared A. Lentini· 1 shared A. Shaw· 1 shared B. Reinius· 1 shared F. Fördös· 1 shared I. Rocamonde Lago· 1 shared I. T. Hoffecker· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

B. Högberg

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Notch engagement by Jag1 nanoscale clusters indicates a force-independent mode of activation

I. Smyrlaki, F. Fördös, I. Rocamonde Lago, Y. Wang, A. Lentini, V. C. Luca, B. Reinius, A. I. Teixeira, B. Högberg

This study shows that Notch receptors can be activated by multivalent Jag1 ligand clusters without requiring mechanical force, using iPSc-derived cells and DNA origami patterns.

bioRxiv · Nov 22, 2022Cell Biology

The geometric determinants of programmed antibody migration and binding on multi-antigen substrates

I. T. Hoffecker, A. Shaw, V. Sorokina, I. Smyrlaki, B. Högberg

The paper develops a model to simulate antibody-antigen interactions on patterned surfaces and shows antigen spacing influences antibody migration and binding.

bioRxiv · Oct 12, 2020 · PreprintBiophysics