Metabolic regulation in erythroid differentiation by systemic ketogenesis in fasted mice
W. Ma, Y. Arima, T. Umemoto, T. Yokomizo, Y. Xu, K. Miharada, Y. Tanaka, T. Suda
This study shows that reduced systemic ketogenesis in fasted mice enhances erythroid maturation by boosting fatty acid synthesis and mevalonate pathway with decreased histone acetylation.
bioRxiv · Jun 7, 2023Cell Biology