The Sle1 Cell Wall Amidase Controls Daughter Cell Splitting, Cell Size, and β-Lactam Resistance in Community Acquired Methicillin Resistant Staphylococcus aureus USA300
I. Thalso-Madsen, F. R. Torrubia, L. Xu, A. Petersen, C. Jensen, D. Frees
This study identifies Sle1 as a key factor in β-lactam resistance in MRSA USA300, showing that high Sle1 levels promote cell separation and reduce oxacillin sensitivity.
bioRxiv · Sep 19, 2019 · PreprintMicrobiology