Targeting intracellular Neu1 for Coronavirus Infection Treatment
D. Yang, Y. Wu, I. Turan, J. Keil, K. Li, M. H. Chen, R. Liu, L. Wang, X.-L. Sun, G. Chen
This study identifies Neu1 as a therapeutic target for coronavirus infection by showing its role in sialylation of viral proteins and demonstrates that a Neu1 inhibitor reduces viral replication in vitro and in vivo.
bioRxiv · Sep 9, 2022Microbiology