Author

I. V. Kostopoulos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Chaidos· 2 shared A. Karadimitris· 2 shared A. Katsarou· 2 shared H. W. Auner· 2 shared K. Ponnusamy· 2 shared N. Trasanidis· 2 shared V. S. Caputo· 2 shared X. Xiao· 2 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersCancer Biology

A. Chaidos

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2 papers

Recent·Most cited

Systems medicine dissection of chromosome 1q amplification reveals oncogenic regulatory circuits and informs targeted therapy in cancer

N. Trasanidis, A. Katsarou, K. Ponnusamy, Y.-A. Shen, I. V. Kostopoulos, B. Bergonia, K. Keren, P. Reema, X. Xiao, R. M. Szydlo, P. M. Sabbattini, I. A. Roberts, H. W. Auner, K. N. Naresh, A. Chaidos, , A. Karadimitris

This study identifies oncogenic regulatory circuits driven by chromosome 1q amplification in cancer and proposes targeted therapy strategies using a systems medicine approach.

bioRxiv · Nov 17, 2021Cancer Biology

The innate sensor ZBP1-IRF3 axis regulates cell proliferation in multiple myeloma

K. Ponnusamy, M. M. Tzioni, M. Begum, M. E. Robinson, V. S. Caputo, A. Katsarou, N. Trasanidis, X. Xiao, I. V. Kostopoulos, D. Iskander, I. Roberts, P. Trivedi, H. W. Auner, K. Naresh, A. Chaidos, A. Karadimitris

The paper shows that the ZBP1-IRF3 axis promotes myeloma cell proliferation by activating cell cycle genes instead of type I IFN responses.

bioRxiv · Jun 17, 2020Cancer Biology