Author

N. Trasanidis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. Chaidos· 3 shared A. Karadimitris· 3 shared A. Katsarou· 3 shared H. W. Auner· 3 shared K. Ponnusamy· 3 shared V. S. Caputo· 3 shared X. Xiao· 3 shared I. A. Roberts· 2 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

A. Chaidos

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Systems medicine dissection of chromosome 1q amplification reveals oncogenic regulatory circuits and informs targeted therapy in cancer

N. Trasanidis, A. Katsarou, K. Ponnusamy, Y.-A. Shen, I. V. Kostopoulos, B. Bergonia, K. Keren, P. Reema, X. Xiao, R. M. Szydlo, P. M. Sabbattini, I. A. Roberts, H. W. Auner, K. N. Naresh, A. Chaidos, , A. Karadimitris

This study identifies oncogenic regulatory circuits driven by chromosome 1q amplification in cancer and proposes targeted therapy strategies using a systems medicine approach.

bioRxiv · Nov 17, 2021Cancer Biology

The innate sensor ZBP1-IRF3 axis regulates cell proliferation in multiple myeloma

K. Ponnusamy, M. M. Tzioni, M. Begum, M. E. Robinson, V. S. Caputo, A. Katsarou, N. Trasanidis, X. Xiao, I. V. Kostopoulos, D. Iskander, I. Roberts, P. Trivedi, H. W. Auner, K. Naresh, A. Chaidos, A. Karadimitris

The paper shows that the ZBP1-IRF3 axis promotes myeloma cell proliferation by activating cell cycle genes instead of type I IFN responses.

bioRxiv · Jun 17, 2020Cancer Biology

Anopheles coluzzii stearoyl-CoA desaturase is essential for adult female survival and reproduction upon blood feeding

Z. Ferdous, S. Fuchs, V. Behrends, N. Trasanidis, D. Vlachou, G. K. Christophides

This study shows that SCD1 is critical for Anopheles coluzzii female survival and reproduction after blood feeding, as its disruption leads to metabolic dysregulation and immune activation.

bioRxiv · Jun 14, 2020Microbiology

Over-accessible chromatin links myeloma initiating genetic events to oncogenic transcriptomes and aberrant transcription factor regulatory networks

J. Alvarez-Benayas, A. Katsarou, N. Trasanidis, A. Chaidos, P. C. May, K. Ponnusamy, X. Xiao, M. Bua, M. Atta, I. A. Roberts, H. W. Auner, E. Hatjiharissi, M. Papaioannou, V. S. Caputo, I. M. Sudbery, A. Karadimitris

The paper links myeloma initiating genetic events to chromatin accessibility and oncogenic transcriptomes, identifying critical enhancers regulating CCND2 expression.

bioRxiv · Jun 11, 2020 · PreprintCancer Biology