A Role for Steroid 5α-reductase 1 in Vascular Remodelling During Endometrial Decidualisation
I. W. Shaw, P. M. Kirkwood, D. Rebourcet, F. L. Cousins, R. J. Ainslie, D. E. W. Livingstone, L. B. Smith, P. T. K. Saunders, D. A. Gibson
This study shows that steroid 5α-reductase 1 is essential for vascular remodelling during endometrial decidualisation in vivo, with androgen signalling via the VEGF pathway playing a key role.
bioRxiv · May 30, 2022 · PreprintPhysiology