Author

D. A. Gibson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Physiology· 4 Immunology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 5 Approach:experimental assay· 5 Organism:mouse· 4 Assay:scRNA-seq· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2

Frequent Co-Authors

P. M. Kirkwood· 3 shared P. T. Saunders· 3 shared F. Collins· 2 shared N. C. Henderson· 2 shared O. Kelepouri· 2 shared P. Saunders· 2 shared R. Dobie· 2 shared A. Esnal Zufiaurre· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersPhysiology

P. M. Kirkwood

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

A Role for Steroid 5α-reductase 1 in Vascular Remodelling During Endometrial Decidualisation

I. W. Shaw, P. M. Kirkwood, D. Rebourcet, F. L. Cousins, R. J. Ainslie, D. E. W. Livingstone, L. B. Smith, P. T. K. Saunders, D. A. Gibson

This study shows that steroid 5α-reductase 1 is essential for vascular remodelling during endometrial decidualisation in vivo, with androgen signalling via the VEGF pathway playing a key role.

bioRxiv · May 30, 2022 · PreprintPhysiology

Single cell RNA sequencing and lineage tracing confirm mesenchyme to epithelial transformation (MET) contributes to repair of the endometrium at menstruation

P. M. Kirkwood, D. A. Gibson, I. Shaw, R. Dobie, O. Kelepouri, N. C. Henderson, P. T. Saunders

This study identifies a novel population of PDGFRβ+ mesenchymal cells that undergo mesenchyme-to-epithelial transformation during endometrial repair, contributing to tissue regeneration.

bioRxiv · Dec 20, 2021Physiology

Single cell RNA sequencing redefines the mesenchymal cell landscape of mouse endometrium

P. M. Kirkwood, D. A. Gibson, J. R. Smith, J. R. Wilson-Kanamori, O. Kelepouri, A. Esnal-Zufiaurre, R. Dobie, N. C. Henderson, P. T. Saunders

This study uses single-cell RNA sequencing to redefine the mesenchymal cell landscape in mouse endometrium, identifying five subpopulations including pericytes, vascular smooth muscle cells, and three distinct fibroblast subtypes.

bioRxiv · Aug 20, 2020Physiology

Peritoneal macrophage phenotype correlates with pain scores in women with suspected endometriosis

D. A. Gibson, F. Collins, B. De Leo, A. W. Hotne, P. Saunders

The paper examines peritoneal macrophage populations in women with suspected endometriosis and finds their phenotypes correlate with pelvic pain severity.

bioRxiv · Jul 31, 2020 · PreprintImmunology

Origin and microenvironment contribute to the sexually dimorphic phenotype and function of peritoneal macrophages.

C. C. Bain, D. A. Gibson, N. J. Steers, K. Boufea, P. A. Louwe, C. Doherty, V. Huici, R. Gentek, M. Magalhaes-Pinto, M. Bajenoff, C. Benezech, D. Dockrell, P. T. Saunders, N. Batadar, S. J. Jenkins

This study shows that sex and age influence peritoneal macrophage behavior through bone marrow replenishment and microenvironment signals, affecting disease resistance.

bioRxiv · Nov 14, 2019Immunology

Profiling the expression and function of ER46 in human endometrial tissues and uterine NK cells

D. A. Gibson, A. Esnal Zufiaurre, C. Bajo Santos, F. Collins, H. Critchley, P. Saunders

This study investigates the expression and function of ER46 in human endometrial tissues and uterine NK cells, finding that ER46 is expressed in these tissues and regulates uNK cell motility.

bioRxiv · Sep 23, 2019 · PreprintPhysiology