Brainstem GLP-1 neurons modulate physiological satiation and drive sustained weight loss in obese mice
Wanqing Jiang, Cecilia Skoug, Ian Rodrigues, Ernesto Ciabatti, Fiona Mary Gribble, Frank M. Reimann, Daniel I. Brierley, Marie K. Holt, Stefan Trapp
This study shows that chronic activation of GLP-1 neurons in the brainstem reduces food intake and causes sustained weight loss in obese mice.
Molecular Metabolism · Mar 4, 2026Peer-reviewedNeuroscience