Inês Lopes

Unravelling the Transcriptomic Symphony of Sarcopenia: Key Pathways and Hub Genes Altered by Muscle Ageing and Caloric Restriction Revealed by RNA Sequencing

This study uses RNA sequencing to identify gene expression changes in aged muscle and how caloric restriction affects these changes, revealing key pathways and hub genes involved in sarcopenia.

Human Ageing Genomic Resources: updates on key databases in ageing research

The paper updates six databases in the Human Ageing Genomic Resources (HAGR) focusing on genes, drugs, and genetic variants related to ageing and longevity.

Positive selection and enhancer evolution shaped lifespan and body mass in great apes

The paper identifies genes and enhancers associated with lifespan and body mass in great apes through evolutionary and molecular analysis.

GeneFriends 2021: Updated co-expression databases and tools for human and mouse genes and transcripts

GeneFriends 2021 updates co-expression networks for human and mouse genes using RNA-seq data from 46,475 and 34,322 samples, respectively.

Gene size matters: What determines gene length in the human genome?

This study investigates factors influencing gene length in the human genome, finding correlations with SNPs, introns, protein size, and tissue-specific expression, and linking gene length to functional roles in development and disease.