Daniela Tejada-Martínez

CAR-T cells targeting uPAR selectively ablate pathogenic microglia while sparing neurons, enabling precision immunotherapy for ALS.

The paper identifies genomic features that enable SVA transposons to function as cis-regulatory elements in human pluripotent stem cells, showing their impact on gene expression.

The paper identifies genes and enhancers associated with lifespan and body mass in great apes through evolutionary and molecular analysis.

This study presents the first genome annotation of a capuchin monkey and identifies genes under positive selection related to longevity, brain development, and adaptation to diverse environments.

The paper curates a database of senescence-associated genes and performs systems biology analyses to identify novel regulators and pathways of cellular senescence.