Diogo Barardo

The paper evaluates the DrugAge database, finding poor reporting quality and inconsistent effect sizes in anti-aging preclinical studies across species.

This study introduces DoliClock, a lipid-based aging clock that identifies accelerated aging in neurological disorders like autism and schizophrenia.

This study compares the anti-ageing effects of a multi-ingredient nutraceutical and a senolytic intervention in old mice, finding both extend lifespan similarly but differ in healthspan benefits.

The paper updates six databases in the Human Ageing Genomic Resources (HAGR) focusing on genes, drugs, and genetic variants related to ageing and longevity.

The paper shows that aging and senescence increase transposon expression through transcriptional readthrough and intron retention, not autonomous transposon activity.

SynergyAge curates genetic and lifespan data from animal models with multiple longevity-modulating interventions to explore synergistic and antagonistic gene interactions.

This study identifies metabolic dysfunction, particularly in the TCA cycle, as an early and causative event in Alzheimer's disease using a transgenic C. elegans model.

This paper updates the Human Ageing Genomic Resources (HAGR), presenting its five databases and their functionalities for studying ageing and longevity.